WSURF Case 545
Serotonin Agents for Cancer Treatment
Summary
Although serotonin is characterized as a neurotransmitter, serotonin transporters have been found in many non-neural cells, including cancer cells. Its function in non-neural cells has not been fully elucidated. However, the widespread distribution of transporters suggests that the effect of serotonergic drugs are pleiotropic and can be considered unpredictable. Within this theme, a novel type of treatment for melanoma utilizing the selective serotonin reuptake inhibitor, fluoxetine (Prozac) has been discovered by researchers at Washington State University.
Applications & Advantages
- Inhibits growth in vitro at physiological concentrations
- Decreases frequency of metastatic foci
- Prevents weight los and loss in body fat (cachexia).
- Proven physiological properties- No gross toxicity
IP Status
This technology is protected by a published US Patent. Exclusive rights are available.
For more information about this technology please contact WSURF:
1610 NE Eastgate Blvd, Suite 650
Pullman, WA 99164
Phone: (509) 335-5526
Fax: (509) 335-7237
wsurf@wsu.edu
